Adenocarcinoma of the lung with positive epidermal growth factor receptor mutation in pregnancy

Gina Amanda; Agus Dwi Susanto; Dicky Soehardiman; Dianiati Kusumo Sutoyo; Yuyun Lisnawati; Boy Busmar; Erlang Samoedro; Elisna Syahruddin; ANDIKA CHANDRA PUTRA

doi:10.4103/0970-2113.217574

Adenocarcinoma of the lung with positive epidermal growth factor receptor mutation in pregnancy

Gina Amanda, Agus Dwi Susanto, Dicky Soehardiman, Dianiati Kusumo Sutoyo, Yuyun Lisnawati, Boy Busmar, Erlang Samoedro, Elisna Syahruddin, ANDIKA CHANDRA PUTRA

Research output: Contribution to journal › Article › peer-review

Abstract

Lung cancer during pregnancy is a rare condition. We report a case of 28-year-old nonsmoker female, who was admitted to our hospital with massive left pleural effusion in the 21^st week of gestation. Chest radiograph showed total left hemithorax opacity with contralateral mediastinal deviation. Pleural biopsy and cytological examination of pleural fluid revealed adenocarcinoma invasion with positive epidermal growth factor receptor mutation status. Cesarean section was performed at 32 weeks of pregnancy, and targeted therapy was given to this patient after delivery. Computed tomography of the thorax showed a mass lesion in the left hemithorax with liver metastases. Unfortunately, the patient died 10 days after delivery.

Original language	English
Pages (from-to)	548-551
Number of pages	4
Journal	Lung India
Volume	34
Issue number	6
DOIs	https://doi.org/10.4103/0970-2113.217574
Publication status	Published - 1 Nov 2017

Keywords

Adenocarcinoma
lung cancer
mutation
pleural effusion
pregnancy

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10.4103/0970-2113.217574

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title = "Adenocarcinoma of the lung with positive epidermal growth factor receptor mutation in pregnancy",

abstract = "Lung cancer during pregnancy is a rare condition. We report a case of 28-year-old nonsmoker female, who was admitted to our hospital with massive left pleural effusion in the 21st week of gestation. Chest radiograph showed total left hemithorax opacity with contralateral mediastinal deviation. Pleural biopsy and cytological examination of pleural fluid revealed adenocarcinoma invasion with positive epidermal growth factor receptor mutation status. Cesarean section was performed at 32 weeks of pregnancy, and targeted therapy was given to this patient after delivery. Computed tomography of the thorax showed a mass lesion in the left hemithorax with liver metastases. Unfortunately, the patient died 10 days after delivery.",

keywords = "Adenocarcinoma, lung cancer, mutation, pleural effusion, pregnancy",

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T1 - Adenocarcinoma of the lung with positive epidermal growth factor receptor mutation in pregnancy

AU - Amanda, Gina

AU - Susanto, Agus Dwi

AU - Soehardiman, Dicky

AU - Sutoyo, Dianiati Kusumo

AU - Lisnawati, Yuyun

AU - Busmar, Boy

AU - Samoedro, Erlang

AU - Syahruddin, Elisna

AU - PUTRA, ANDIKA CHANDRA

PY - 2017/11/1

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N2 - Lung cancer during pregnancy is a rare condition. We report a case of 28-year-old nonsmoker female, who was admitted to our hospital with massive left pleural effusion in the 21st week of gestation. Chest radiograph showed total left hemithorax opacity with contralateral mediastinal deviation. Pleural biopsy and cytological examination of pleural fluid revealed adenocarcinoma invasion with positive epidermal growth factor receptor mutation status. Cesarean section was performed at 32 weeks of pregnancy, and targeted therapy was given to this patient after delivery. Computed tomography of the thorax showed a mass lesion in the left hemithorax with liver metastases. Unfortunately, the patient died 10 days after delivery.

AB - Lung cancer during pregnancy is a rare condition. We report a case of 28-year-old nonsmoker female, who was admitted to our hospital with massive left pleural effusion in the 21st week of gestation. Chest radiograph showed total left hemithorax opacity with contralateral mediastinal deviation. Pleural biopsy and cytological examination of pleural fluid revealed adenocarcinoma invasion with positive epidermal growth factor receptor mutation status. Cesarean section was performed at 32 weeks of pregnancy, and targeted therapy was given to this patient after delivery. Computed tomography of the thorax showed a mass lesion in the left hemithorax with liver metastases. Unfortunately, the patient died 10 days after delivery.

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KW - pleural effusion

KW - pregnancy

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Adenocarcinoma of the lung with positive epidermal growth factor receptor mutation in pregnancy

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Keywords

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