Activity salivary bacteria of acute lymphoblastic leukemia children in chemotherapy phase

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Abstract

Objective: The objective of this study was to investigate the differences activity of salivary Streptococcus mutans bacteria in children suffer acute lymphoblastic leukemia (ALL) in phase of chemotherapy, induction, intensification/consolidation, and maintenance. Methods: This study was a laboratory observational, and cross-sectional method, conducted 19 ALL children in phase of chemotherapy, induction, intensification/consolidation, and maintenance. 2 mm of dental plaque was collected from mesiobuccal first permanent molar and incubated for 48 h at 37°C, and the bacterial activity of S. mutans measured by Cariostat. Results: Odds ratio analysis among chemotherapy phase of induction, intensification/consolidation, and maintenance is not significant (p>0.05) differences. Conclusion: The highest activity bacteria of S. mutans were found in the induction phase.

Original languageEnglish
Pages (from-to)47-49
Number of pages3
JournalAsian Journal of Pharmaceutical and Clinical Research
Volume11
Issue number3
DOIs
Publication statusPublished - 1 Mar 2018

Keywords

  • ALL
  • Activity bacteria
  • Chemotherapy phase
  • Streptococcus mutans

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