Activity of Natural Compound Pothos tener Wall on Aeromonas hydrophila Infection to Prevent of Antibiotics

Media Fitri Isma Nugraha; Dwi Asih Kurniati; Sri Rukmini; Imam Taukhid; Hessy Novita; Bejo Slamet; Ikhsan Khasani; Dwi Budiyanto Trisnoharjono; Muh Alias L. Rajamuddin; Berna Elya

doi:10.18517/ijaseit.13.6.19182

Activity of Natural Compound Pothos tener Wall on Aeromonas hydrophila Infection to Prevent of Antibiotics

Media Fitri Isma Nugraha, Dwi Asih Kurniati, Sri Rukmini, Imam Taukhid, Hessy Novita, Bejo Slamet, Ikhsan Khasani, Dwi Budiyanto Trisnoharjono, Muh Alias L. Rajamuddin, Berna Elya

Department of Pharmacy

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

This study aims to discover how influential Photos tener Wall is as an anti-bacterial treatment for Aeromonas hydrophila. Methods: Cyprinus Carpio were reared for 28 days, and on the 29th and 30th days before Aeromonas hydrophila infection, the fish were adequately fasted. On the 31st day, they were intramuscularly challenged with A. hydrophila (105 CFU/mL) (the first day in A. hydrophila infection). The treatments given were (I) immersed trial with fresh (live) P tener Wall: (H1) Immersed with 15 g of P. tener Wall plant, (H2) Immersed with 30 g of P. tener Wall plant, and (H3) Immersed with 60 g of P. tener; (II) feeding trials in which the treatments given were (P1) 2% of P. tener Wall powder mixed with 1 kg commercial diet and (P2) 4% of P. tener Wall powder mixed with 1 kg commercial diet; Experiment III combined the best results from experiment I (H2) and experiment II (P2) and Oxytetracycline 5 g/kg feed as a control antibiotic. The result obtained was that the treatment of 30 g of fresh P. tener Wall or adding 4% simplicial P. tener Wall in the diet could increase koi fish’s immune response and resistance to A. Hydrophila has a survival rate that reaches 100%. This treatment has the same effect as using antibiotic Oxytetracycline 5 g/kg of feed. An important aspect for further research is that P. tener wall can be tested on other fish diseases caused by bacteria or fungi.

Original language	English
Pages (from-to)	1999-2008
Number of pages	10
Journal	International Journal on Advanced Science, Engineering and Information Technology
Volume	13
Issue number	6
DOIs	https://doi.org/10.18517/ijaseit.13.6.19182
Publication status	Published - 2023

Keywords

Cyprinus carpio
GC-MS
immune response
LC-MS
Pothos tener wall

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10.18517/ijaseit.13.6.19182

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Nugraha, M. F. I., Kurniati, D. A., Rukmini, S., Taukhid, I., Novita, H., Slamet, B., Khasani, I., Trisnoharjono, D. B., Rajamuddin, M. A. L., & Elya, B. (2023). Activity of Natural Compound Pothos tener Wall on Aeromonas hydrophila Infection to Prevent of Antibiotics. International Journal on Advanced Science, Engineering and Information Technology, 13(6), 1999-2008. https://doi.org/10.18517/ijaseit.13.6.19182

@article{f07670b6cb4f4accb82dc0141a003735,

title = "Activity of Natural Compound Pothos tener Wall on Aeromonas hydrophila Infection to Prevent of Antibiotics",

abstract = "This study aims to discover how influential Photos tener Wall is as an anti-bacterial treatment for Aeromonas hydrophila. Methods: Cyprinus Carpio were reared for 28 days, and on the 29th and 30th days before Aeromonas hydrophila infection, the fish were adequately fasted. On the 31st day, they were intramuscularly challenged with A. hydrophila (105 CFU/mL) (the first day in A. hydrophila infection). The treatments given were (I) immersed trial with fresh (live) P tener Wall: (H1) Immersed with 15 g of P. tener Wall plant, (H2) Immersed with 30 g of P. tener Wall plant, and (H3) Immersed with 60 g of P. tener; (II) feeding trials in which the treatments given were (P1) 2% of P. tener Wall powder mixed with 1 kg commercial diet and (P2) 4% of P. tener Wall powder mixed with 1 kg commercial diet; Experiment III combined the best results from experiment I (H2) and experiment II (P2) and Oxytetracycline 5 g/kg feed as a control antibiotic. The result obtained was that the treatment of 30 g of fresh P. tener Wall or adding 4% simplicial P. tener Wall in the diet could increase koi fish{\textquoteright}s immune response and resistance to A. Hydrophila has a survival rate that reaches 100%. This treatment has the same effect as using antibiotic Oxytetracycline 5 g/kg of feed. An important aspect for further research is that P. tener wall can be tested on other fish diseases caused by bacteria or fungi.",

keywords = "Cyprinus carpio, GC-MS, immune response, LC-MS, Pothos tener wall",

author = "Nugraha, {Media Fitri Isma} and Kurniati, {Dwi Asih} and Sri Rukmini and Imam Taukhid and Hessy Novita and Bejo Slamet and Ikhsan Khasani and Trisnoharjono, {Dwi Budiyanto} and Rajamuddin, {Muh Alias L.} and Berna Elya",

note = "Publisher Copyright: {\textcopyright} (2023) IJASEIT is licensed under a Creative Commons Attribution-Share Alike 4.0 International License.",

year = "2023",

doi = "10.18517/ijaseit.13.6.19182",

language = "English",

volume = "13",

pages = "1999--2008",

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Nugraha, MFI, Kurniati, DA, Rukmini, S, Taukhid, I, Novita, H, Slamet, B, Khasani, I, Trisnoharjono, DB, Rajamuddin, MAL & Elya, B 2023, 'Activity of Natural Compound Pothos tener Wall on Aeromonas hydrophila Infection to Prevent of Antibiotics', International Journal on Advanced Science, Engineering and Information Technology, vol. 13, no. 6, pp. 1999-2008. https://doi.org/10.18517/ijaseit.13.6.19182

TY - JOUR

T1 - Activity of Natural Compound Pothos tener Wall on Aeromonas hydrophila Infection to Prevent of Antibiotics

AU - Nugraha, Media Fitri Isma

AU - Kurniati, Dwi Asih

AU - Rukmini, Sri

AU - Taukhid, Imam

AU - Novita, Hessy

AU - Slamet, Bejo

AU - Khasani, Ikhsan

AU - Trisnoharjono, Dwi Budiyanto

AU - Rajamuddin, Muh Alias L.

AU - Elya, Berna

N1 - Publisher Copyright: © (2023) IJASEIT is licensed under a Creative Commons Attribution-Share Alike 4.0 International License.

PY - 2023

Y1 - 2023

N2 - This study aims to discover how influential Photos tener Wall is as an anti-bacterial treatment for Aeromonas hydrophila. Methods: Cyprinus Carpio were reared for 28 days, and on the 29th and 30th days before Aeromonas hydrophila infection, the fish were adequately fasted. On the 31st day, they were intramuscularly challenged with A. hydrophila (105 CFU/mL) (the first day in A. hydrophila infection). The treatments given were (I) immersed trial with fresh (live) P tener Wall: (H1) Immersed with 15 g of P. tener Wall plant, (H2) Immersed with 30 g of P. tener Wall plant, and (H3) Immersed with 60 g of P. tener; (II) feeding trials in which the treatments given were (P1) 2% of P. tener Wall powder mixed with 1 kg commercial diet and (P2) 4% of P. tener Wall powder mixed with 1 kg commercial diet; Experiment III combined the best results from experiment I (H2) and experiment II (P2) and Oxytetracycline 5 g/kg feed as a control antibiotic. The result obtained was that the treatment of 30 g of fresh P. tener Wall or adding 4% simplicial P. tener Wall in the diet could increase koi fish’s immune response and resistance to A. Hydrophila has a survival rate that reaches 100%. This treatment has the same effect as using antibiotic Oxytetracycline 5 g/kg of feed. An important aspect for further research is that P. tener wall can be tested on other fish diseases caused by bacteria or fungi.

AB - This study aims to discover how influential Photos tener Wall is as an anti-bacterial treatment for Aeromonas hydrophila. Methods: Cyprinus Carpio were reared for 28 days, and on the 29th and 30th days before Aeromonas hydrophila infection, the fish were adequately fasted. On the 31st day, they were intramuscularly challenged with A. hydrophila (105 CFU/mL) (the first day in A. hydrophila infection). The treatments given were (I) immersed trial with fresh (live) P tener Wall: (H1) Immersed with 15 g of P. tener Wall plant, (H2) Immersed with 30 g of P. tener Wall plant, and (H3) Immersed with 60 g of P. tener; (II) feeding trials in which the treatments given were (P1) 2% of P. tener Wall powder mixed with 1 kg commercial diet and (P2) 4% of P. tener Wall powder mixed with 1 kg commercial diet; Experiment III combined the best results from experiment I (H2) and experiment II (P2) and Oxytetracycline 5 g/kg feed as a control antibiotic. The result obtained was that the treatment of 30 g of fresh P. tener Wall or adding 4% simplicial P. tener Wall in the diet could increase koi fish’s immune response and resistance to A. Hydrophila has a survival rate that reaches 100%. This treatment has the same effect as using antibiotic Oxytetracycline 5 g/kg of feed. An important aspect for further research is that P. tener wall can be tested on other fish diseases caused by bacteria or fungi.

KW - Cyprinus carpio

KW - GC-MS

KW - immune response

KW - LC-MS

KW - Pothos tener wall

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DO - 10.18517/ijaseit.13.6.19182

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AN - SCOPUS:85183933934

SN - 2088-5334

VL - 13

SP - 1999

EP - 2008

JO - International Journal on Advanced Science, Engineering and Information Technology

JF - International Journal on Advanced Science, Engineering and Information Technology

IS - 6

ER -

Activity of Natural Compound Pothos tener Wall on Aeromonas hydrophila Infection to Prevent of Antibiotics

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Keywords

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