Accuracy of Centor scoring system in diagnosing group a-beta haemolytic streptococcal (GABHS) infection

Niken lestari Poerbonegoro, Joanna erin Hanrahan, Indira Amelia, Viharsyah aulia Akbar, Raditya putra Djohan, Ika dwi Mayangsari, Dini widiarni Widodo

Research output: Contribution to journalLiterature reviewpeer-review

Abstract

Background: At present, the standard examination for diagnosing streptococcal upper respiratory tract infection is throat culture. As throat culture is time-consuming and relatively expensive, efforts are made to develop certain criteria that will still lead to proper diagnosis and rational use of antibiotics, that is Centor score. Even so, the accuracy of Centor score is still debatable. Purpose: To provide evidence on the accuracy of Centor scoring system compared to throat culture in diagnosing GABHS upper respiratory tract infection. Case Report: A 25-years old male came to primary health care with primary complain of sore throat. Centor score was used to diagnose GABHS infection and as a guide to give antibiotics. Clinical question: “In patients with sore throat, how accurate is the Centor score compared to throat culture in diagnosing Group A Beta-Haemolytic Streptococcal (GABHS) Infection?” Methods: Literature searching was conducted through 4 databases. Critical appraisal based on the Centre of Evidence-Based Medicine (CEBM)-University of Oxford University, Diagnostic Critical Appraisal Sheet and Systematic Review Sheet. Results: All the selected studies were considered valid. They revealed a high specificity, low sensitivity, high negative predictive value (NPV), and low positive predictive value (PPV) in the importance aspect assessment. The Centor scoring system was applicable to our patient. It was available, affordable, and accurate in adult patients, yet less accurate in children. Conclusion: In conclusion,Patient with sore throat and suspicion of GABHS infection could be diagnosed with Centor scoring system as the first line diagnosis in primary care and as a guide to whether to give giving antibiotics or not.
Original languageEnglish
Pages (from-to)53-61
JournalOTO RHINO LARYNGOLOGICA INDONESIANAOTO RHINO LARYNGOLOGICA INDONESIANA
Volume52
Issue number1
DOIs
Publication statusPublished - 4 Jul 2022

Keywords

  • Streptococcal
  • Centor Score
  • Throat Culture
  • Diagnosis

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