A systematic review of the importance of chemoprophylaxis and immunoprophylaxis in subclinical case of leprosy that can reduce the incidence and the transmission of leprosy

Nurrachmat Mulianto, Ardelia Dyah Ayu Puspita Sari, Harijono Kariosentono, Ferry Arrochman, Ria Margiana

Research output: Contribution to journalArticlepeer-review

Abstract

Leprosy is a condition that is believed to be caused by Mycobacterium leprae abbreviated as m-leprae. There is no medication known to treat leprosy. However, leprosy progression and transmission can be done by the use of chemoprophylaxis and immunoprophylaxis. The study is a systematic review of available literature on diseases and the preventive measures employed to prevent leprosy. The study question was developed based on prevention, intervention, comparison, outcome, and the study design incorporated in the study. The survey conducted through searches in different medical and nursing databases to get materials relevant to the study. Pubmed, Cinahl, among other databases, were screened to provide documents addressed to the PICOS question. Over three hundred articles were found in the screened databases, but only four were considered for this study. Inclusion and exclusion were based on keywords of the reviews that were found online. Chemoprophylaxis and immunoprophylaxis are essential in preventing the development and progression of leprosy. Chemoprophylaxis and immunoprophylaxis act as immunization agents to people who contact infected people regularly.

Original languageEnglish
Pages (from-to)709-715
Number of pages7
JournalEuropean Journal of Molecular and Clinical Medicine
Volume7
Issue number11
Publication statusPublished - Sep 2020

Keywords

  • Chemoprophylaxis
  • Immunoprophylaxis
  • Leprosy
  • Transmission of leprosy

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