A modification of Johnson score as predictive value of sperm retrieval in non-obstructive azoospermia infertile men

Silvia W. Lestari, Debby Aditya, Gita Pratama, Kanadi Sumapradja, Ria Margiana

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Non obstructive azoospermia (NOA), due to testicular failure, revealed up to 60% of all cases of azoospermia. One of the decisive NOA management is performing testicular sperm extraction (TESE) with success rates approximately 50%, yet a factor for predicting TESE quality is still insufficient. The objective of this work was to assess and develop an alternative outcome predictor of TESE procedure in NOA. To this purpose, a retrospective case series was performed to 31 patients with azoospermia undergone TESE in 2016-2018. Collected data included a clinical history, testicular volume, hormone levels and testicular histology were analyzed following sperm retrieval. The findings resulted in 14 patients had obstructive azoospermia (OA) and 17 patients had NOA. The results showed that all of OA patients had positive sperm retrieval, while NOA patients were 50%. The analyzed data performed that the normal value of testicular size, FSH and the high Johnson score (≥8) were the finest predictor of positive sperm retrieval. In conclusion, the modification of Johnson score may be utilized as a promising predictor of successful or positive surgical sperm retrieval in NOA.

Original languageEnglish
Title of host publication3rd Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices
Subtitle of host publicationProceedings of the International Symposium of Biomedical Engineering, ISBE 2018
EditorsPraswasti P.D.K. Wulan, Misri Gozan, Sotya Astutiningsih, Ghiska Ramahdita, Radon Dhelika, Prasetyanugraheni Kreshanti
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735418226
DOIs
Publication statusPublished - 9 Apr 2019
Event3rd International Symposium of Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2018 - Jakarta, Indonesia
Duration: 6 Aug 20188 Aug 2018

Publication series

NameAIP Conference Proceedings
Volume2092
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference3rd International Symposium of Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2018
CountryIndonesia
CityJakarta
Period6/08/188/08/18

Keywords

  • Johnson score
  • NOA
  • sperm retrieval
  • testicular histopathology

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    Lestari, S. W., Aditya, D., Pratama, G., Sumapradja, K., & Margiana, R. (2019). A modification of Johnson score as predictive value of sperm retrieval in non-obstructive azoospermia infertile men. In P. P. D. K. Wulan, M. Gozan, S. Astutiningsih, G. Ramahdita, R. Dhelika, & P. Kreshanti (Eds.), 3rd Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices: Proceedings of the International Symposium of Biomedical Engineering, ISBE 2018 [030019] (AIP Conference Proceedings; Vol. 2092). American Institute of Physics Inc.. https://doi.org/10.1063/1.5096723