A mini systematic review: Eucheuma cottonii, a red algae, as a radiosensitizer?

Tisa P. Putri; Ida A.T.K. Dewi; Tiara B.M. Permata; Endang Nuryadi; Henry Kodrat; Heri Wibowo; Melva Louisa; Soehartati A. Gondhowiardjo

doi:10.26538/tjnpr/v5i1.2

A mini systematic review: Eucheuma cottonii, a red algae, as a radiosensitizer?

Tisa P. Putri, Ida A.T.K. Dewi, Tiara B.M. Permata, Endang Nuryadi, Henry Kodrat, Heri Wibowo, Melva Louisa, Soehartati A. Gondhowiardjo

Research output: Contribution to journal › Review article › peer-review

3 Citations (Scopus)

Abstract

Radiosensitizers assist radiotherapy in providing greater tumor inactivation. Currently there is a search for natural radiosensitizer components which are expected to provide lesser side effects than chemical radiosensitizers. Eucheuma cottonii is a plant with antioxidant and anti-tumor effects. This review aims to search for the potential use of Eucheuma cottonii as a radiosensitizer. This is a mixed review study, where the main component is a systematic review and then followed by a narrative review. This review suggests that Eucheuma cottonii has the potential to become a radiosensitizer, by interfering with the cell cycle control mechanisms and reactivation of p53. Further research is needed to explore the synergistic effect of the combined use of radiotherapy and Eucheuma cottonii.

Original language	English
Pages (from-to)	7-15
Number of pages	9
Journal	Tropical Journal of Natural Product Research
Volume	5
Issue number	1
DOIs	https://doi.org/10.26538/tjnpr/v5i1.2
Publication status	Published - Jan 2021

Keywords

Anti-tumour
Eucheuma cottonii
Immunomodulator
Radiosensitizer

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.26538/tjnpr/v5i1.2

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@article{14c04d7cc5ad487797dce502e59c3e6f,

title = "A mini systematic review: Eucheuma cottonii, a red algae, as a radiosensitizer?",

abstract = "Radiosensitizers assist radiotherapy in providing greater tumor inactivation. Currently there is a search for natural radiosensitizer components which are expected to provide lesser side effects than chemical radiosensitizers. Eucheuma cottonii is a plant with antioxidant and anti-tumor effects. This review aims to search for the potential use of Eucheuma cottonii as a radiosensitizer. This is a mixed review study, where the main component is a systematic review and then followed by a narrative review. This review suggests that Eucheuma cottonii has the potential to become a radiosensitizer, by interfering with the cell cycle control mechanisms and reactivation of p53. Further research is needed to explore the synergistic effect of the combined use of radiotherapy and Eucheuma cottonii.",

keywords = "Anti-tumour, Eucheuma cottonii, Immunomodulator, Radiosensitizer",

author = "Putri, {Tisa P.} and Dewi, {Ida A.T.K.} and Permata, {Tiara B.M.} and Endang Nuryadi and Henry Kodrat and Heri Wibowo and Melva Louisa and Gondhowiardjo, {Soehartati A.}",

note = "Funding Information: We appreciated and thank International Publication Grant from Universitas Indonesia for the support throughout the projects. Publisher Copyright: {\textcopyright} 2021 Putri et al. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",

year = "2021",

month = jan,

doi = "10.26538/tjnpr/v5i1.2",

language = "English",

volume = "5",

pages = "7--15",

journal = "Tropical Journal of Natural Product Research",

issn = "2616-0684",

publisher = "Faculty of Pharmacy, University of Benin",

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T2 - Eucheuma cottonii, a red algae, as a radiosensitizer?

AU - Putri, Tisa P.

AU - Dewi, Ida A.T.K.

AU - Permata, Tiara B.M.

AU - Nuryadi, Endang

AU - Kodrat, Henry

AU - Wibowo, Heri

AU - Louisa, Melva

AU - Gondhowiardjo, Soehartati A.

N1 - Funding Information: We appreciated and thank International Publication Grant from Universitas Indonesia for the support throughout the projects. Publisher Copyright: © 2021 Putri et al. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.

PY - 2021/1

Y1 - 2021/1

N2 - Radiosensitizers assist radiotherapy in providing greater tumor inactivation. Currently there is a search for natural radiosensitizer components which are expected to provide lesser side effects than chemical radiosensitizers. Eucheuma cottonii is a plant with antioxidant and anti-tumor effects. This review aims to search for the potential use of Eucheuma cottonii as a radiosensitizer. This is a mixed review study, where the main component is a systematic review and then followed by a narrative review. This review suggests that Eucheuma cottonii has the potential to become a radiosensitizer, by interfering with the cell cycle control mechanisms and reactivation of p53. Further research is needed to explore the synergistic effect of the combined use of radiotherapy and Eucheuma cottonii.

AB - Radiosensitizers assist radiotherapy in providing greater tumor inactivation. Currently there is a search for natural radiosensitizer components which are expected to provide lesser side effects than chemical radiosensitizers. Eucheuma cottonii is a plant with antioxidant and anti-tumor effects. This review aims to search for the potential use of Eucheuma cottonii as a radiosensitizer. This is a mixed review study, where the main component is a systematic review and then followed by a narrative review. This review suggests that Eucheuma cottonii has the potential to become a radiosensitizer, by interfering with the cell cycle control mechanisms and reactivation of p53. Further research is needed to explore the synergistic effect of the combined use of radiotherapy and Eucheuma cottonii.

KW - Anti-tumour

KW - Eucheuma cottonii

KW - Immunomodulator

KW - Radiosensitizer

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U2 - 10.26538/tjnpr/v5i1.2

DO - 10.26538/tjnpr/v5i1.2

M3 - Review article

AN - SCOPUS:85100549316

SN - 2616-0684

VL - 5

SP - 7

EP - 15

JO - Tropical Journal of Natural Product Research

JF - Tropical Journal of Natural Product Research

IS - 1

ER -

A mini systematic review: Eucheuma cottonii, a red algae, as a radiosensitizer?

Abstract

Keywords

UN SDGs

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