TY - JOUR
T1 - A mathematical model for chemotherapy paradoxical reaction in Tuberculosis transmission
AU - Rahmawati, Febriana Tri
AU - Bustamam, Alhadi
AU - Aldila, Dipo
N1 - Funding Information:
This research is funded by Universitas Indonesia with PITTA research grant 2018 scheme with contract Number ID: 2252/UN2.R3.1/HKP.05.00/2018.
Publisher Copyright:
© Published under licence by IOP Publishing Ltd.
PY - 2018/12/4
Y1 - 2018/12/4
N2 - An SEIR with the age-class model is analyzed in this article to understand how paradoxical reaction in Tuberculosis (TB) treatment impact the success of TB control program. Mathematical model analysis of equilibrium points and the basic reproduction number of the model are analyzed. A numerical experiment about the dependency of basic reproduction number respect to the change of other parameters is given to give an illustration of how the paradoxical reaction might impact the success of chemotherapy intervention on TB. From the numerical investigation, we find that the paradoxical reaction plays an important role to determine the TB will coexist or disappear.
AB - An SEIR with the age-class model is analyzed in this article to understand how paradoxical reaction in Tuberculosis (TB) treatment impact the success of TB control program. Mathematical model analysis of equilibrium points and the basic reproduction number of the model are analyzed. A numerical experiment about the dependency of basic reproduction number respect to the change of other parameters is given to give an illustration of how the paradoxical reaction might impact the success of chemotherapy intervention on TB. From the numerical investigation, we find that the paradoxical reaction plays an important role to determine the TB will coexist or disappear.
UR - http://www.scopus.com/inward/record.url?scp=85058330361&partnerID=8YFLogxK
U2 - 10.1088/1742-6596/1108/1/012057
DO - 10.1088/1742-6596/1108/1/012057
M3 - Conference article
AN - SCOPUS:85058330361
VL - 1108
JO - Journal of Physics: Conference Series
JF - Journal of Physics: Conference Series
SN - 1742-6588
IS - 1
M1 - 012057
T2 - 2nd Mathematics, Informatics, Science and Education International Conference, MISEIC 2018
Y2 - 21 July 2018
ER -