A mathematical model for chemotherapy paradoxical reaction in Tuberculosis transmission

Febriana Tri Rahmawati, Alhadi Bustamam, Dipo Aldila

Research output: Contribution to journalConference articlepeer-review

4 Citations (Scopus)


An SEIR with the age-class model is analyzed in this article to understand how paradoxical reaction in Tuberculosis (TB) treatment impact the success of TB control program. Mathematical model analysis of equilibrium points and the basic reproduction number of the model are analyzed. A numerical experiment about the dependency of basic reproduction number respect to the change of other parameters is given to give an illustration of how the paradoxical reaction might impact the success of chemotherapy intervention on TB. From the numerical investigation, we find that the paradoxical reaction plays an important role to determine the TB will coexist or disappear.

Original languageEnglish
Article number012057
JournalJournal of Physics: Conference Series
Issue number1
Publication statusPublished - 4 Dec 2018
Event2nd Mathematics, Informatics, Science and Education International Conference, MISEIC 2018 - Surabaya, Indonesia
Duration: 21 Jul 2018 → …


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