TY - JOUR
T1 - A glimpse on the function of chitosan as a dental hemostatic agent
AU - Lestari, Widya
AU - Yusry, Wan Nur Aisyah Wan
AU - Haris, Muhammad Salahuddin
AU - Jaswir, Irwandi
AU - Idrus, Erik
N1 - Funding Information:
The authors would like to thank the Ministry of Education Malaysia for funding this study (grant number: FRGS/1/2019/SKK14/UIAM/02/2 ).
Publisher Copyright:
© 2020 The Authors
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/11
Y1 - 2020/11
N2 - Managing a bleeding patient can be a challenge during dental surgery. Profuse hemorrhage due to platelet defects, coagulation disorders, vascular anomalies, medication-induced patients, as well as inherited bleeding ailments result in soft tissue hematoma, septic shock, compromised airway, and in some severe cases, death could occur. A vast array of surgical hemostatic agents are available to stop bleeding, including chitosan-based hemostatic agents. Chitosan has an advantage over other topical hemostatic materials for its ability to promote shorter bleeding times and assist in healing. Massive behind-the-scene research and development efforts are ongoing to increase the performance of chitosan as a hemostatic agent. Numerous studies on chitosan use in dental hemostasis have registered it as being safe, biodegradable, biocompatible, promoting healing, antimicrobial and bioactive. This article reviews the application of chitosan in managing hemostasis in dental patients.
AB - Managing a bleeding patient can be a challenge during dental surgery. Profuse hemorrhage due to platelet defects, coagulation disorders, vascular anomalies, medication-induced patients, as well as inherited bleeding ailments result in soft tissue hematoma, septic shock, compromised airway, and in some severe cases, death could occur. A vast array of surgical hemostatic agents are available to stop bleeding, including chitosan-based hemostatic agents. Chitosan has an advantage over other topical hemostatic materials for its ability to promote shorter bleeding times and assist in healing. Massive behind-the-scene research and development efforts are ongoing to increase the performance of chitosan as a hemostatic agent. Numerous studies on chitosan use in dental hemostasis have registered it as being safe, biodegradable, biocompatible, promoting healing, antimicrobial and bioactive. This article reviews the application of chitosan in managing hemostasis in dental patients.
KW - Chitosan
KW - Dental hemostatic agent
UR - http://www.scopus.com/inward/record.url?scp=85096956540&partnerID=8YFLogxK
U2 - 10.1016/j.jdsr.2020.09.001
DO - 10.1016/j.jdsr.2020.09.001
M3 - Review article
AN - SCOPUS:85096956540
SN - 1882-7616
VL - 56
SP - 147
EP - 154
JO - Japanese Dental Science Review
JF - Japanese Dental Science Review
IS - 1
ER -