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  • 2020
  • 2019
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  • Usman Sumo Friend
2020

Discovery of GPX4 inhibitor by molecular docking simulation as a potential ferroptosis inducer

Fatonah, A., Tambunan, U. S. F., Pamungkas, W. O., Dewanto, G. L. & Wicaksono, I. S., 15 Feb 2020, In : Biointerface Research in Applied Chemistry. 10, 1, p. 4929-4933 5 p.

Research output: Contribution to journalArticle

Discovery of natural product compounds as dengue virus NS5 methyltransferase inhibitor candidate through in silico method

Bagastama, A. R., Alkaff, A. H. & Tambunan, U. S. F., 1 Jan 2020, Symposium of Materials Science and Chemistry II. Wahyuningsih, T. D., Roto, R., Siswanta, D., Adnan, R., Commeiras, L., Triyana, K., Triyana, K., Kartini, I. & Motuzas, J. (eds.). Trans Tech Publications Ltd, p. 270-276 7 p. (Key Engineering Materials; vol. 840 KEM).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access

Discovery of novel α-amylase inhibitors as type two diabetes mellitus therapy through fragment-based drug design

Hidayat, M. F., Ningsih, E. G., Alkaff, A. H. & Tambunan, U. S. F., 1 Jan 2020, Symposium of Materials Science and Chemistry II. Wahyuningsih, T. D., Roto, R., Siswanta, D., Adnan, R., Commeiras, L., Triyana, K., Triyana, K., Kartini, I. & Motuzas, J. (eds.). Trans Tech Publications Ltd, p. 237-244 8 p. (Key Engineering Materials; vol. 840 KEM).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Flexible molecular docking simulation of peptide compounds as inhibitor of GluI host protein for dengue fever therapy

Stephanie, F., Alkaff, A. H. & Tambunan, U. S. F., 2 Jun 2020, 14th Joint Conference on Chemistry 2019. Rahmawati, F., Saraswati, T. E., Nugrahaningtyas, K. D., Marliyana, S. D. & Kusumaningsih, T. (eds.). American Institute of Physics Inc., 020031. (AIP Conference Proceedings; vol. 2237).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Identification of natural product compounds as NS5 RDRP inhibitor for dengue virus serotype 1-4 through in silico analysis

Putra, H. H., Saragih, M., Yulianti & Tambunan, U. S. F., 2 Jun 2020, 14th Joint Conference on Chemistry 2019. Rahmawati, F., Saraswati, T. E., Nugrahaningtyas, K. D., Marliyana, S. D. & Kusumaningsih, T. (eds.). American Institute of Physics Inc., 020030. (AIP Conference Proceedings; vol. 2237).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Inhibition of Primed Ebola Virus Glycoprotein by Peptide Compound Conjugated to HIV-1 Tat Peptide Through a Virtual Screening Approach

Alkaff, A. H., Saragih, M., Nasution, M. A. F. & Tambunan, U. S. F., 1 Jan 2020, Computational Intelligence Methods for Bioinformatics and Biostatistics - 15th International Meeting, CIBB 2018, Revised Selected Papers. Raposo, M., Ribeiro, P., Sério, S., Staiano, A. & Ciaramella, A. (eds.). Springer, p. 153-165 13 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11925 LNBI).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

In silico identification of peptide as epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer treatment

Imana, S. N., Ningsih, E. G. & Tambunan, U. S. F., 1 Jan 2020, In : Pakistan Journal of Biological Sciences. 23, 4, p. 567-574 8 p.

Research output: Contribution to journalArticle

Open Access

Pharmacophore Modelling, Virtual Screening, and Molecular Docking Simulations of Natural Product Compounds as Potential Inhibitors of Ebola Virus Nucleoprotein

Nasution, M. A. F., Alkaff, A. H., Rizki, I. F., Bakri, R. & Tambunan, U. S. F., 1 Jan 2020, Computational Intelligence Methods for Bioinformatics and Biostatistics - 15th International Meeting, CIBB 2018, Revised Selected Papers. Raposo, M., Ribeiro, P., Sério, S., Staiano, A. & Ciaramella, A. (eds.). Springer, p. 166-178 13 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11925 LNBI).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Role of immunoinformatics in accelerating epitope-based vaccine development against dengue virus

Alkaff, A. H., Saragih, M., Fardiansyah, M. A. & Tambunan, U. S. F., 1 Jan 2020, In : Open Biochemistry Journal. 14, 1, p. 9-18 10 p.

Research output: Contribution to journalArticle

Open Access

Utilization of flavonoid compounds as HER2 tyrosine kinase inhibitor in breast cancer using fragment-based drug design

Fleming, V. J., Saragih, M. & Tambunan, U. S. F., 1 Jan 2020, Symposium of Materials Science and Chemistry II. Wahyuningsih, T. D., Roto, R., Siswanta, D., Adnan, R., Commeiras, L., Triyana, K., Triyana, K., Kartini, I. & Motuzas, J. (eds.). Trans Tech Publications Ltd, p. 230-236 7 p. (Key Engineering Materials; vol. 840 KEM).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Virtual screening based on pharmacophore to discover host ER alpha- glucosidase II inhibitor for dengue therapy

Ariavianti, E., Stephanie, F. & Tambunan, U. S. F., 1 Jan 2020, Symposium of Materials Science and Chemistry II. Wahyuningsih, T. D., Roto, R., Siswanta, D., Adnan, R., Commeiras, L., Triyana, K., Triyana, K., Kartini, I. & Motuzas, J. (eds.). Trans Tech Publications Ltd, p. 221-229 9 p. (Key Engineering Materials; vol. 840 KEM).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2019

A mutant variant of nix gene on γ-irradiated Aedes Aegypti as a male-determination factor

Ernawan, B., Surniyantoro, H. N. E., Sugoro, I. & Friend, U. S., 1 Mar 2019, In : Biodiversitas. 20, 3, p. 893-899 7 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Discovery of biogenic-based compound as potential heat-shock protein 90 inhibitor through fragment-based drug design

Putra, H. H., Saragih, M., Fardiansyah, M. A. N., Bakri, R. & Tambunan, U. S. F., 3 May 2019, In : IOP Conference Series: Materials Science and Engineering. 509, 1, 012081.

Research output: Contribution to journalConference article

Open Access

Discovery of Novel Alpha-Amylase Inhibitors for Type II Diabetes Mellitus Through the Fragment-Based Drug Design

Yulianti, Kantale, A. C. B. & Tambunan, U. S. F., 1 Jan 2019, Bioinformatics and Biomedical Engineering - 7th International Work-Conference, IWBBIO 2019, Proceedings. Ortuño, F., Valenzuela, O., Rojas, I., Rojas, F. & Ortuño, F. (eds.). Springer Verlag, p. 25-35 11 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11465 LNBI).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Discovery of novel DNMT-1 inhibitor by fragment-based drug design as a potential breast cancer treatment

Saragih, M., Alkaff, A. H., Natalia, A. H., Istiqomah, I. N. & Friend Tambunan, U. S., 1 Jan 2019, In : International Journal of GEOMATE. 17, 62, p. 41-46 6 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Fragment-Based Drug Design to Discover Novel Inhibitor of Dipeptidyl Peptidase-4 (DPP-4) as a Potential Drug for Type 2 Diabetes Therapy

Ningsih, E. G., Hidayat, M. F. & Tambunan, U. S. F., 1 Jan 2019, Bioinformatics and Biomedical Engineering - 7th International Work-Conference, IWBBIO 2019, Proceedings. Ortuño, F., Valenzuela, O., Rojas, I., Rojas, F. & Ortuño, F. (eds.). Springer Verlag, p. 14-24 11 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11465 LNBI).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fragment-Based drug design to inhibit DNA Methyltransferase 1 (DNMT1) for breast cancer therapy

Natalia, A. H., Alkaff, A. H., Saragih, M., Istiqomah, I. N. & Tambunan, U. S. F., 1 Jan 2019, In : International Journal of GEOMATE. 17, 62, p. 35-40 6 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Identification novel peptides conjugated to hiv1 tat peptide to inhibit ebola virus entry by targeting niemann pick C1 protein

Saragih, M., Stephanie, F., Alkaff, A. H. & Tambunan, U. S. F., Oct 2019, Proceedings - 2019 IEEE 19th International Conference on Bioinformatics and Bioengineering, BIBE 2019. Institute of Electrical and Electronics Engineers Inc., p. 44-49 6 p. 8941623. (Proceedings - 2019 IEEE 19th International Conference on Bioinformatics and Bioengineering, BIBE 2019).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

In silico identification of 2-oxo-1,3-thiazolidine derivatives as novel inhibitor candidate of class II histone deacetylase (HDAC) in cervical cancer treatment

Friend, U. S., Parikesit, A. A., Ghifari, A. S. & Satriyanto, C. P., 1 Feb 2019, In : Arabian Journal of Chemistry. 12, 2, p. 272-288 17 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)
Open Access

Pharmacophore-based virtual screening and molecular docking simulation of flavonoids as smoothened protein inhibitor of Hedgehog signaling pathways

Nasution, M. A. F., Stephanie, F. & Tambunan, U. S. F., 4 Nov 2019, Proceedings of the 4th International Symposium on Current Progress in Mathematics and Sciences, ISCPMS 2018. Mart, T., Triyono, D. & Anggraningrum, I. T. (eds.). American Institute of Physics Inc., 020060. (AIP Conference Proceedings; vol. 2168).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access

Pharmacophore-based virtual screening and molecular docking simulation of terpenoid compounds as the inhibitor of sonic hedgehog protein for colorectal cancer therapy

Ekawati, M. M., Fardiansyah Nasution, M. A., Siregar, S., Rizki, I. F. & Friend Tambunan, U. S., 3 May 2019, In : IOP Conference Series: Materials Science and Engineering. 509, 1, 012075.

Research output: Contribution to journalConference article

Open Access

Screening of potential northern african natural product compounds as dengue virus NS5 methyltransferase inhibitor: An in silico approach

Stephanie, F., Saragih, M., Alkaff, A. H., Nasution, M. A. F. & Tambunan, U. S. F., Oct 2019, Proceedings - 2019 IEEE 19th International Conference on Bioinformatics and Bioengineering, BIBE 2019. Institute of Electrical and Electronics Engineers Inc., p. 215-220 6 p. 8941961. (Proceedings - 2019 IEEE 19th International Conference on Bioinformatics and Bioengineering, BIBE 2019).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Strategies of tuberculosis-HIV vaccines design using immunoinformatic approach

Fatonah, A., Satrio Wicaksono, I. & Tambunan, U. S. F., 1 Jan 2019, In : OnLine Journal of Biological Sciences. 19, 2, p. 110-116 7 p.

Research output: Contribution to journalArticle

Structure-based virtual screening of Indonesian natural product compounds as Ebola virus VP30 protein inhibitors

Tio, G. A., Bernadette, A., Nasution, M. A. F., Sitadevi, P. A. & Tambunan, U. S. F., 1 Jan 2019, In : International Journal of GEOMATE. 17, 61, p. 208-214 7 p.

Research output: Contribution to journalArticle

Open Access

The development of novel HPV drugs by HDAC inhibitor based upon applied bioinformatics tool and their specialized algorithm

Puspitasari, R. D., Tambunan, U. S. F. & Dewanto, G. L., 15 Oct 2019, In : Biointerface Research in Applied Chemistry. 9, 5, p. 4428-4432 5 p.

Research output: Contribution to journalReview article

Open Access

Virtual screening of natural products as an inhibitor of DNA methyltransferase 1 enzyme for breast cancer disease

Istiqomah, I. N., Alkaff, A. H., Saragih, M., Natalia, A. H. & Friend Tambunan, U. S., 3 May 2019, In : IOP Conference Series: Materials Science and Engineering. 509, 1, 012052.

Research output: Contribution to journalConference article

Open Access
1 Citation (Scopus)
2018

Assessment of Drug Binding Potential of Pockets in the NS2B/NS3 Dengue Virus Protein

Amelia, F., Iryani, Sari, P. Y., Parikesit, A. A., Bakri, R., Toepak, E. P. & Friend, U. S., 2 May 2018, In : IOP Conference Series: Materials Science and Engineering. 349, 1, 012021.

Research output: Contribution to journalConference article

Open Access

Changes in germs: A potential preemptive strike against the next pandemic

Friend, U. S., 1 Jan 2018, In : Journal of Medical Sciences (Faisalabad). 18, 1, p. 48-55 8 p.

Research output: Contribution to journalReview article

Open Access

Computational insight into flavonoid-based compound for inhibition activity on SAH-binding site of dengue virus NS5 methyltransferase: Molecular docking and in silico ADME-Tox studies

Siregar, S., Marnolia, A., Nasution, M. A. F., Kirani, D. & Friend, U. S., 22 Oct 2018, Proceedings of the 3rd International Symposium on Current Progress in Mathematics and Sciences 2017, ISCPMS 2017. Yuniati, R., Mart, T., Anggraningrum, I. T., Triyono, D. & Sugeng, K. A. (eds.). American Institute of Physics Inc., 020063. (AIP Conference Proceedings; vol. 2023).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Computational protein design in green chemistry

Parikesit, A. A. & Friend, U. S., 1 Jul 2018, In : Rasayan Journal of Chemistry. 11, 3, p. 1133-1138 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Computational screening of flavonoid based inhibitor targeting DENV NS5 methyltransferase

Marnolia, A., Toepak, E. P., Siregar, S., Kirani, D. & Friend, U. S., 22 Oct 2018, Proceedings of the 3rd International Symposium on Current Progress in Mathematics and Sciences 2017, ISCPMS 2017. Yuniati, R., Mart, T., Anggraningrum, I. T., Triyono, D. & Sugeng, K. A. (eds.). American Institute of Physics Inc., 020070. (AIP Conference Proceedings; vol. 2023).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Discovery of Indonesian natural products as potential inhibitor of Ebola virus VP40 through molecular docking simulation

Nasution, M. A. F., Alkaff, A. H. & Friend, U. S., 22 Oct 2018, Proceedings of the 3rd International Symposium on Current Progress in Mathematics and Sciences 2017, ISCPMS 2017. Yuniati, R., Mart, T., Anggraningrum, I. T., Triyono, D. & Sugeng, K. A. (eds.). American Institute of Physics Inc., 020055. (AIP Conference Proceedings; vol. 2023).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Ebola viral protein 24 (VP24) inhibitor discovery by in silico fragment-based design

Friend, U. S., Siregar, S. & Toepak, E. P., 1 Jan 2018, In : International Journal of GEOMATE. 15, 49, p. 59-64 6 p.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)
Open Access
7 Citations (Scopus)

Fragment-based drug design of host endoplasmic reticulum α-glucosidase II inhibitors for dengue fever treatment using an integrated computational approach

Toepak, E. P., Nasution, M. A. F. & Friend, U. S., 22 Oct 2018, Proceedings of the 3rd International Symposium on Current Progress in Mathematics and Sciences 2017, ISCPMS 2017. Yuniati, R., Mart, T., Anggraningrum, I. T., Triyono, D. & Sugeng, K. A. (eds.). American Institute of Physics Inc., 020066. (AIP Conference Proceedings; vol. 2023).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Fragment-based lead compound design to inhibit Ebola VP35 through computational studies

Marnolia, A., Toepak, E. P. & Friend, U. S., 1 Jan 2018, In : International Journal of GEOMATE. 15, 49, p. 65-71 7 p.

Research output: Contribution to journalArticle

Open Access

Identification of natural products as an inhibitor of β-OG pocket binder of dengue virus envelope protein using fragment-based drug design and molecular docking approach

Friend, U. S. & Alkaff, A. H., 22 Oct 2018, Proceedings of the 3rd International Symposium on Current Progress in Mathematics and Sciences 2017, ISCPMS 2017. Yuniati, R., Mart, T., Anggraningrum, I. T., Triyono, D. & Sugeng, K. A. (eds.). American Institute of Physics Inc., 020059. (AIP Conference Proceedings; vol. 2023).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Molecular Docking Simulation of Neuraminidase Influenza A Subtype H1N1 with Potential Inhibitor of Disulfide Cyclic Peptide (DNY, NNY, LRL)

Putra, R. P., Imaniastuti, R., Nasution, M. A. F., Kirani, D. & Friend, U. S., 2 May 2018, In : IOP Conference Series: Materials Science and Engineering. 349, 1, 012052.

Research output: Contribution to journalConference article

Open Access

Novel inhibitors of T315I mutant BCR-ABL1 tyrosine kinase for chronic myeloid leukemia disease through fragment-based drug design

Anindita, S., Marnolia, A., Putra, H. H., Haikal, M. C. & Friend, U. S., 1 Jan 2018, Bioinformatics Research and Applications - 14th International Symposium, ISBRA 2018, Proceedings. Zhang, F., Zhang, S., Cai, Z. & Skums, P. (eds.). Springer Verlag, p. 185-190 6 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10847 LNBI).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Screening of sonic hedgehog (Shh) inhibitors in the hedgehog signaling pathway from traditional chinese medicine (TCM) database through structure-based pharmacophore design

Rizki, I. F., Nasution, M. A. F., Siregar, S., Ekawati, M. M. & Friend, U. S., 1 Jan 2018, Bioinformatics Research and Applications - 14th International Symposium, ISBRA 2018, Proceedings. Zhang, F., Zhang, S., Cai, Z. & Skums, P. (eds.). Springer Verlag, p. 179-184 6 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10847 LNBI).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Searching of flavonoid compounds as a new antiviral for Sudan Ebolavirus glycoprotein using in silico methods

Putra, R. P., Alkaff, A. H., Nasution, M. A. F., Kantale, A. C. B. & Friend, U. S., 1 Jan 2018, In : International Journal of GEOMATE. 15, 49, p. 78-84 7 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2017

Bioinformatics Approach to Screening and Developing Drug against Ebola

Friend, U. S., 2017, Advances in Ebola Control. Intech Open

Research output: Chapter in Book/Report/Conference proceedingChapter

Effects of gamma irradiation dose-rate on sterile male Aedesaegypti

Ernawan, B., Friend, U. S., Sugoro, I. & Sasmita, H. I., 26 Jun 2017, Proceeding of International Biology Conference 2016: Biodiversity and Biotechnology for Human Welfare. American Institute of Physics Inc., 020010. (AIP Conference Proceedings; vol. 1854).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
4 Citations (Scopus)

Exposing the molecular screening method of indonesian natural products derivate as drug candidates for cervical cancer

Friend, U. S., Parikesit, A. A., Nasution, M. A. F., Hapsari, A. & Kirani, D., 1 Jun 2017, In : Iranian Journal of Pharmaceutical Research. 16, 3, p. 1115-1129 15 p., 25.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Identification of novel Ebola virus (EBOV) VP24 inhibitor from Indonesian natural products through in silico drug design approach

Friend, U. S. & Nasution, M. A. F., 10 Jul 2017, International Symposium on Current Progress in Mathematics and Sciences 2016, ISCPMS 2016: Proceedings of the 2nd International Symposium on Current Progress in Mathematics and Sciences 2016. Sugeng, K. A., Triyono, D. & Mart, T. (eds.). American Institute of Physics Inc., 030091. (AIP Conference Proceedings; vol. 1862).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
11 Citations (Scopus)

In silico design of fragment-based drug targeting host processing α-glucosidase i for dengue fever

Toepak, E. P. & Friend, U. S., 17 Feb 2017, In : IOP Conference Series: Materials Science and Engineering. 172, 1, 012017.

Research output: Contribution to journalConference article

Open Access
6 Citations (Scopus)

In silico mutation analysis of non-structural protein-5 (NS5) dengue virus

Puspitasari, R. D. & Friend, U. S., 2 May 2017, In : IOP Conference Series: Materials Science and Engineering. 188, 1, 012043.

Research output: Contribution to journalConference article

Open Access
1 Citation (Scopus)

In silico study of guanosine triphosphate (GTP) and ribavirin derivatives as the inhibitor for NS5 methyltransferase of dengue virus

Friend, U. S., Parikesit, A. A., Wardani, F., Nasution, M. A. F. & Kirani, D., 1 Jan 2017, In : Rasayan Journal of Chemistry. 10, 3, p. 910-921 12 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)