(7e)-3-(4-methoxyphenyl)-7-[(4-methoxyphenyl)methylidene]-4,5,6,7-tetrahydro-3ah-indazole

Hariyanti Hariyanti; Arry Yanuar; Kusmardi Kusmardi; Hayun Hayun

doi:10.3390/M1162

(7e)-3-(4-methoxyphenyl)-7-[(4-methoxyphenyl)methylidene]-4,5,6,7-tetrahydro-3ah-indazole

Hariyanti Hariyanti, Arry Yanuar, Kusmardi Kusmardi, Hayun Hayun

Department of Pharmacy

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Indazole derivatives are well known to have various pharmacological activities. We synthesized a novel derivative of indazole, namely (7E)-3-(4-methoxyphenyl)-7-[(4-methoxyphenyl)methylidene]-4,5,6,7-tetrahydro-3aH-indazole by condensation reaction between 3-(4-methoxyphenyl)-3,3a,4,5,6,7-hexahydro-2H-indazole and 4-methoxy-benzaldehyde in good yield (61%).

Original language	English
Article number	M1162
Pages (from-to)	1-4
Number of pages	4
Journal	MolBank
Volume	2020
Issue number	4
DOIs	https://doi.org/10.3390/M1162
Publication status	Published - Dec 2020

Keywords

Condensation
Hexahydro-indazole
Indazole derivatives
P-methoxybenzaldehyde
Tetrahydro-indazole

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10.3390/M1162

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@article{8dbee097bfc24cacbf86b218404f34c3,

title = "(7e)-3-(4-methoxyphenyl)-7-[(4-methoxyphenyl)methylidene]-4,5,6,7-tetrahydro-3ah-indazole",

abstract = "Indazole derivatives are well known to have various pharmacological activities. We synthesized a novel derivative of indazole, namely (7E)-3-(4-methoxyphenyl)-7-[(4-methoxyphenyl)methylidene]-4,5,6,7-tetrahydro-3aH-indazole by condensation reaction between 3-(4-methoxyphenyl)-3,3a,4,5,6,7-hexahydro-2H-indazole and 4-methoxy-benzaldehyde in good yield (61%).",

keywords = "Condensation, Hexahydro-indazole, Indazole derivatives, P-methoxybenzaldehyde, Tetrahydro-indazole",

author = "Hariyanti Hariyanti and Arry Yanuar and Kusmardi Kusmardi and Hayun Hayun",

note = "Funding Information: Funding: This research was funded by Doctoral Dissertation Research Grant, the Ministry of Research and Technology/National Research Agency, Republic of Indonesia, fiscal year 2020 (Grant No.: NKB-0373/UN2.RST/ HKP.05.00/2020). The APC was supported by Universitas Indonesia. Funding Information: Acknowledgments: Thanks the Ministry of Research and Technology/National Research Agency, Republic of Indonesia, for the funding support of this study, the Chemical Research Center of the Indonesian Institute of Sciences, Serpong, Indonesia, for recording NMR and HR-MS spectra; and Universitas Muhammadiyah DR. HAMKA, Jakarta, for the doctoral program (for Hariyanti). Publisher Copyright: {\textcopyright} 2020 by the authors. Licensee MDPI, Basel, Switzerland. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",

year = "2020",

month = dec,

doi = "10.3390/M1162",

language = "English",

volume = "2020",

pages = "1--4",

journal = "MolBank",

issn = "1422-8599",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "4",

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TY - JOUR

T1 - (7e)-3-(4-methoxyphenyl)-7-[(4-methoxyphenyl)methylidene]-4,5,6,7-tetrahydro-3ah-indazole

AU - Hariyanti, Hariyanti

AU - Yanuar, Arry

AU - Kusmardi, Kusmardi

AU - Hayun, Hayun

N1 - Funding Information: Funding: This research was funded by Doctoral Dissertation Research Grant, the Ministry of Research and Technology/National Research Agency, Republic of Indonesia, fiscal year 2020 (Grant No.: NKB-0373/UN2.RST/ HKP.05.00/2020). The APC was supported by Universitas Indonesia. Funding Information: Acknowledgments: Thanks the Ministry of Research and Technology/National Research Agency, Republic of Indonesia, for the funding support of this study, the Chemical Research Center of the Indonesian Institute of Sciences, Serpong, Indonesia, for recording NMR and HR-MS spectra; and Universitas Muhammadiyah DR. HAMKA, Jakarta, for the doctoral program (for Hariyanti). Publisher Copyright: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

PY - 2020/12

Y1 - 2020/12

N2 - Indazole derivatives are well known to have various pharmacological activities. We synthesized a novel derivative of indazole, namely (7E)-3-(4-methoxyphenyl)-7-[(4-methoxyphenyl)methylidene]-4,5,6,7-tetrahydro-3aH-indazole by condensation reaction between 3-(4-methoxyphenyl)-3,3a,4,5,6,7-hexahydro-2H-indazole and 4-methoxy-benzaldehyde in good yield (61%).

AB - Indazole derivatives are well known to have various pharmacological activities. We synthesized a novel derivative of indazole, namely (7E)-3-(4-methoxyphenyl)-7-[(4-methoxyphenyl)methylidene]-4,5,6,7-tetrahydro-3aH-indazole by condensation reaction between 3-(4-methoxyphenyl)-3,3a,4,5,6,7-hexahydro-2H-indazole and 4-methoxy-benzaldehyde in good yield (61%).

KW - Condensation

KW - Hexahydro-indazole

KW - Indazole derivatives

KW - P-methoxybenzaldehyde

KW - Tetrahydro-indazole

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U2 - 10.3390/M1162

DO - 10.3390/M1162

M3 - Article

AN - SCOPUS:85094559302

SN - 1422-8599

VL - 2020

SP - 1

EP - 4

JO - MolBank

JF - MolBank

IS - 4

M1 - M1162

ER -

(7e)-3-(4-methoxyphenyl)-7-[(4-methoxyphenyl)methylidene]-4,5,6,7-tetrahydro-3ah-indazole

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