Abstract
Background:
Hypertension is a common risk factor of stroke. Carotid intima media thickening (IMT) is an early sign of atherosclerosis in stroke patient.
Objective:
This study aimed to found IMT cut off difference in hypertension and non-hypertension stroke patient.
Methods:
This was a retrospective cross-sectional study using stroke registry in Neurology Outpatient Clinic, RSUPN Dr. Cipto Mangunkusumo, Jakarta, in January–December 2020. Hypertension was measured clinically, whereas IMT was measured using carotid duplex. Subjects were categorized into hypertension and non-hypertension. Patients with diabetes mellitus were excluded. Univariate analysis and Mann-Whitney test were performed to evaluate the differences.
Result:
Of 108 subjects with the mean age of 56.13 + 10.98 years, 73 (67,6%) subjects were male. The proportion of hypertension was 53.7%. The median of left CIMT in hypertension and non-hypertension group were 0.955 (0.5–1.55) and 0.8 (0.4–1.1) (p < 0.001). The median of right IMT in hypertension and non-hypertension group were 0.9 (0.4–1.6) and 0.8 (0.4–1) (p = 0.038).
Discussion:
Hypertension may cause sheer stress and inflammation at bilateral endothelium common carotid artery (CCA), which predisposed to atherosclerosis and manifested into IMT. The current guideline recommended IMT threshold value of 1 mm to be associated with greater risk to develop a new vascular event. In this study, we found that median of IMT was 0.9 mm in stroke with hypertension patients, which was lower than currently recommended cut off.
Conclusion:
IMT 0.9 mm should be considered as a new value to start secondary stroke prevention in hypertension patients.
Hypertension is a common risk factor of stroke. Carotid intima media thickening (IMT) is an early sign of atherosclerosis in stroke patient.
Objective:
This study aimed to found IMT cut off difference in hypertension and non-hypertension stroke patient.
Methods:
This was a retrospective cross-sectional study using stroke registry in Neurology Outpatient Clinic, RSUPN Dr. Cipto Mangunkusumo, Jakarta, in January–December 2020. Hypertension was measured clinically, whereas IMT was measured using carotid duplex. Subjects were categorized into hypertension and non-hypertension. Patients with diabetes mellitus were excluded. Univariate analysis and Mann-Whitney test were performed to evaluate the differences.
Result:
Of 108 subjects with the mean age of 56.13 + 10.98 years, 73 (67,6%) subjects were male. The proportion of hypertension was 53.7%. The median of left CIMT in hypertension and non-hypertension group were 0.955 (0.5–1.55) and 0.8 (0.4–1.1) (p < 0.001). The median of right IMT in hypertension and non-hypertension group were 0.9 (0.4–1.6) and 0.8 (0.4–1) (p = 0.038).
Discussion:
Hypertension may cause sheer stress and inflammation at bilateral endothelium common carotid artery (CCA), which predisposed to atherosclerosis and manifested into IMT. The current guideline recommended IMT threshold value of 1 mm to be associated with greater risk to develop a new vascular event. In this study, we found that median of IMT was 0.9 mm in stroke with hypertension patients, which was lower than currently recommended cut off.
Conclusion:
IMT 0.9 mm should be considered as a new value to start secondary stroke prevention in hypertension patients.
| Original language | English |
|---|---|
| Pages | e8 |
| DOIs | |
| Publication status | Published - 1 May 2021 |
| Event | 15th InaSH Scientific Meeting: Recent Condition of Hypertension and Beyond - Virtual, Jakarta, Indonesia Duration: 27 Feb 2021 → 28 Feb 2021 |
Other
| Other | 15th InaSH Scientific Meeting |
|---|---|
| Country/Territory | Indonesia |
| City | Jakarta |
| Period | 27/02/21 → 28/02/21 |
