1.34 - Gut Microbiota Dysbiosis in Non-alcoholic Fatty Liver Disease

Cosmas Rinaldi A. Lesmana; Maria S. Paramitha; Irsan Hasan

doi:10.1016/B978-0-12-819265-8.00079-6

1.34 - Gut Microbiota Dysbiosis in Non-alcoholic Fatty Liver Disease

Cosmas Rinaldi A. Lesmana, Maria S. Paramitha, Irsan Hasan

Department of Internal Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Non-alcoholic fatty liver disease (NAFLD) is still and will become a major problem worldwide as its prevalence is increasing. The new proposed term metabolic associated fatty liver disease (MAFLD) has opening the new horizon from the old dominant liver disease to metabolic associated liver disease. Gut microbiota dysbiosis is considered as “a man behind the gun”, not only causing a problem in the gut but also in other organs. Since gut microbiota also has a strong link to metabolic dysfunction, this chapter discusses gut microbiota dysbiosis in NAFLD, starting from the basic science until the most recent clinical evidence.

Original language	English
Title of host publication	Comprehensive Gut Microbiota
Publisher	Elsevier
Pages	475-488
Number of pages	14
Volume	1
ISBN (Electronic)	9780128192658
ISBN (Print)	9780128220368
DOIs	https://doi.org/10.1016/B978-0-12-819265-8.00079-6
Publication status	Published - 1 Jan 2022

Keywords

Diabetes mellitus
Gut dysbiosis
Gut microbiota
Hypertension
Intestinal mucosal barrier
Intra-extra hepatic malignancy
Liver fibrosis
Metabolic syndrome
Non-alcoholic fatty liver disease
Obesity

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/B978-0-12-819265-8.00079-6

Cite this

@inbook{588a4c6992c942229140a2009c55e93e,

title = "1.34 - Gut Microbiota Dysbiosis in Non-alcoholic Fatty Liver Disease",

abstract = "Non-alcoholic fatty liver disease (NAFLD) is still and will become a major problem worldwide as its prevalence is increasing. The new proposed term metabolic associated fatty liver disease (MAFLD) has opening the new horizon from the old dominant liver disease to metabolic associated liver disease. Gut microbiota dysbiosis is considered as “a man behind the gun”, not only causing a problem in the gut but also in other organs. Since gut microbiota also has a strong link to metabolic dysfunction, this chapter discusses gut microbiota dysbiosis in NAFLD, starting from the basic science until the most recent clinical evidence.",

keywords = "Diabetes mellitus, Gut dysbiosis, Gut microbiota, Hypertension, Intestinal mucosal barrier, Intra-extra hepatic malignancy, Liver fibrosis, Metabolic syndrome, Non-alcoholic fatty liver disease, Obesity",

author = "Lesmana, {Cosmas Rinaldi A.} and Paramitha, {Maria S.} and Irsan Hasan",

year = "2022",

month = jan,

day = "1",

doi = "10.1016/B978-0-12-819265-8.00079-6",

language = "English",

isbn = "9780128220368",

volume = "1",

pages = "475--488",

booktitle = "Comprehensive Gut Microbiota",

publisher = "Elsevier",

address = "Netherlands",

}

TY - CHAP

T1 - 1.34 - Gut Microbiota Dysbiosis in Non-alcoholic Fatty Liver Disease

AU - Lesmana, Cosmas Rinaldi A.

AU - Paramitha, Maria S.

AU - Hasan, Irsan

PY - 2022/1/1

Y1 - 2022/1/1

N2 - Non-alcoholic fatty liver disease (NAFLD) is still and will become a major problem worldwide as its prevalence is increasing. The new proposed term metabolic associated fatty liver disease (MAFLD) has opening the new horizon from the old dominant liver disease to metabolic associated liver disease. Gut microbiota dysbiosis is considered as “a man behind the gun”, not only causing a problem in the gut but also in other organs. Since gut microbiota also has a strong link to metabolic dysfunction, this chapter discusses gut microbiota dysbiosis in NAFLD, starting from the basic science until the most recent clinical evidence.

AB - Non-alcoholic fatty liver disease (NAFLD) is still and will become a major problem worldwide as its prevalence is increasing. The new proposed term metabolic associated fatty liver disease (MAFLD) has opening the new horizon from the old dominant liver disease to metabolic associated liver disease. Gut microbiota dysbiosis is considered as “a man behind the gun”, not only causing a problem in the gut but also in other organs. Since gut microbiota also has a strong link to metabolic dysfunction, this chapter discusses gut microbiota dysbiosis in NAFLD, starting from the basic science until the most recent clinical evidence.

KW - Diabetes mellitus

KW - Gut dysbiosis

KW - Gut microbiota

KW - Hypertension

KW - Intestinal mucosal barrier

KW - Intra-extra hepatic malignancy

KW - Liver fibrosis

KW - Metabolic syndrome

KW - Non-alcoholic fatty liver disease

KW - Obesity

UR - http://www.scopus.com/inward/record.url?scp=85151733915&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-819265-8.00079-6

DO - 10.1016/B978-0-12-819265-8.00079-6

M3 - Chapter

AN - SCOPUS:85151733915

SN - 9780128220368

VL - 1

SP - 475

EP - 488

BT - Comprehensive Gut Microbiota

PB - Elsevier

ER -

1.34 - Gut Microbiota Dysbiosis in Non-alcoholic Fatty Liver Disease

Abstract

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this