1.34 - Gut Microbiota Dysbiosis in Non-alcoholic Fatty Liver Disease

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Non-alcoholic fatty liver disease (NAFLD) is still and will become a major problem worldwide as its prevalence is increasing. The new proposed term metabolic associated fatty liver disease (MAFLD) has opening the new horizon from the old dominant liver disease to metabolic associated liver disease. Gut microbiota dysbiosis is considered as “a man behind the gun”, not only causing a problem in the gut but also in other organs. Since gut microbiota also has a strong link to metabolic dysfunction, this chapter discusses gut microbiota dysbiosis in NAFLD, starting from the basic science until the most recent clinical evidence.

Original languageEnglish
Title of host publicationComprehensive Gut Microbiota
PublisherElsevier
Pages475-488
Number of pages14
Volume1
ISBN (Electronic)9780128192658
ISBN (Print)9780128220368
DOIs
Publication statusPublished - 1 Jan 2022

Keywords

  • Diabetes mellitus
  • Gut dysbiosis
  • Gut microbiota
  • Hypertension
  • Intestinal mucosal barrier
  • Intra-extra hepatic malignancy
  • Liver fibrosis
  • Metabolic syndrome
  • Non-alcoholic fatty liver disease
  • Obesity

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