Department of Medical Chemistry Pre Clinic

Research Output 2005 2019

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Article
2019
Open Access
Oldenlandia
Ageratum
Iodoacetates
Anti-Inflammatory Agents
Calgranulin A
Aloe
Optical Coherence Tomography
Wound Healing
Skin
Wounds and Injuries

Cytotoxic activity of ethanol and ethyl acetate extract of kenikir (cosmos caudatus) against cervical cancer cell line (HELA)

Dwira, S., Fadhillah, M. R., Fadilah, F., Azizah, N. N., Putrianingsih, R. & Kusmardi, K., 1 Mar 2019, In : Research Journal of Pharmacy and Technology. 12, 3, p. 1225-1229 5 p.

Research output: Contribution to journalArticle

Uterine Cervical Neoplasms
Ethanol
Cell Line
Chemoradiotherapy
Glycosides
2 Citations (Scopus)
Cartilage Oligomeric Matrix Protein
Matrix Metalloproteinase 13
Disintegrins
Quercetin
Matrix Metalloproteinase 9
2018
Open Access
3,4-Methylenedioxyamphetamine
Zingiberaceae
Estrogen Receptor Modulators
Gossypol
Vascular Endothelial Growth Factor A

Differential scanning calorimeter profiling for the determination of nanoparticle ethanol extract of clove (Syzygium aromaticum L.) toward Michigan cancer foundation-7 human breast cancer cell lines

Fadilah, Abdurrohman, H., Joyo, E. O., Widodo, V. A., Priawan, R. P., Yazid, F., Paramita, R. I. & Purwaningsih, E. H., 1 Oct 2018, In : Asian Journal of Pharmaceutics. 12, 4, p. S1451-S1455

Research output: Contribution to journalArticle

Syzygium
Nanoparticles
Ethanol
Breast Neoplasms
Cell Line
Open Access
Leptin Receptors
Volatile Oils
Cinnamomum
Obesity
Inhalation
Open Access
Ficus
Catenins
Computer Simulation
Colon
Carcinogenesis
Centella
Interleukin-1
Interleukin-4
Computer Simulation
Interleukin-6

In vitro cytotoxicity of the synthesized gallic acid derivatives (N-Alkyl Gallamide) against breast MCF-7 cancer cells

Marcelia, M., Arsianti, A., Chan, J. O. T., Wijoyo, STE. ANO. JULIO., Fadilah, Putrianingsih, R., Azizah, N. N., Bahtiar, A., Tanimoto, H. & Kiyomikakiuchi, 1 Jan 2018, In : Oriental Journal of Chemistry. 34, 5, p. 2268-2272 5 p.

Research output: Contribution to journalArticle

Gallic Acid
MCF-7 Cells
Cytotoxicity
cancer
Breast

In vitro evaluation of seaweed gracilaria verrucosa for cytotoxic activity against cervical HeLa cells

Dewi, M. K., Arsianti, A., Zagloel, C. R. Z., Aziza, Y. A. N., Kurniasari, K. D., Mandasari, B. K. D., Masita, R., Zulfa, F. R., Azizah, N. N. & Putrianingsih, R., 1 Jan 2018, In : Pharmacognosy Journal. 10, 5, p. 1007-1011 5 p.

Research output: Contribution to journalArticle

Open Access
Gracilaria
Seaweed
HeLa Cells
Hexanes
Inhibitory Concentration 50
Open Access
Acetogenins
Annona
Hypoxia-Inducible Factor 1
Pharmaceutical Preparations
Colonic Neoplasms
2 Citations (Scopus)

Molecular docking and dynamic simulation studies of benzoylated emodin into HBV core protein

Firdayani, Arsianti, A., Churiyah & Yanuar, A., 1 Apr 2018, In : Journal of Young Pharmacists. 10, 2, p. s20-s24

Research output: Contribution to journalArticle

Open Access
Molecular Docking Simulation
Emodin
Viral Core Proteins
Molecular Dynamics Simulation
Hepatitis B virus

Molecular dynamic of pinostrobin and pinocembrin from Kaempferia pandurata Roxb. towards estrogen receptor positive (ESR) and estrogen receptor negative (VEGFR) of breast cancer

Fadilah, Edina, B. C., Rahmawati, R. A., Wiyono, L., Erlina, L., Paramita, R. I. & Tedjo, A., 1 Oct 2018, In : Asian Journal of Pharmaceutics. 12, 4, p. S1473-S1480

Research output: Contribution to journalArticle

Zingiberaceae
Molecular Dynamics Simulation
Estrogen Receptors
Breast Neoplasms
Vascular Endothelial Growth Factor A
1 Citation (Scopus)

Novel cinchona alkaloid derivatives as potential antimalarial agents through receptor-inhibitor interaction fingerprint and biosynthesis design

Rosmalena, Prasasty, V. D. & Hanafi, M., 1 Jan 2018, In : Oriental Journal of Chemistry. 34, 5, p. 2643-2650 8 p.

Research output: Contribution to journalArticle

antimalarial agent
Cinchona Alkaloids
alkaloid
Biosynthesis
Antimalarials

Phytochemical analysis and anticancer activity of seaweed gracilaria verrucosa against colorectal HCT-116 cells

Kurniasari, K. D. W. I., Arsianti, A., Nugrahayning Aziza, Y. A., Dyahningrum Mandasari, B. K., Masita, R., Ruhama Zulfa, F., Kusumaning Dewi, M., Zahira Zagloel, C. R., Azizah, N. N. U. R. & Putrianingsih, R., 1 Jan 2018, In : Oriental Journal of Chemistry. 34, 3, p. 1257-1262 6 p.

Research output: Contribution to journalArticle

Open Access
Gracilaria
HCT116 Cells
Seaweed
Phytochemicals
seaweed
1 Citation (Scopus)

Phytochemical test and cytotoxic activity of macroalgae eucheuma cottonii against cervical HeLa cells

Arsianti, A., Aziza, Y. A. N., Kurniasari, K. D., Mandasari, B. K. D., Masita, R., Zulfa, F. R., Dewi, M. K., Zagloel, C. R. Z., Azizah, N. N. & Putrianingsih, R., 1 Jan 2018, In : Pharmacognosy Journal. 10, 5, p. 1012-1017 6 p.

Research output: Contribution to journalArticle

Open Access
Seaweed
Phytochemicals
HeLa Cells
Thin Layer Chromatography
Chloroform
1 Citation (Scopus)
Structure-Activity Relationship
carboxylic acid
Carboxylic Acids
Benzene
Linear regression
1 Citation (Scopus)

Synthesis and anticancer effect of 3,4,5-n-alkyl-benzamides on colon carcinoma HCT- 116 cells

Chan, J. O. T., Arsianti, A., Marcelia, M., Wijoyo, S. J., Fadilah, Putrianingsih, R., Azizah, N. N., Tanimoto, H. & Kakiuchi, K., 1 Jan 2018, In : Oriental Journal of Chemistry. 34, 3, p. 1362-1367 6 p.

Research output: Contribution to journalArticle

Open Access
Benzamides
HCT116 Cells
Colon
Gallic Acid
Carcinoma

Synthesis and cytotoxic activities of hexyl-esters derivatives of gallic acid against MCF-7 cell line

Paramita, R. I., Arsianti, A. & Radji, M., 1 Jan 2018, In : Oriental Journal of Chemistry. 34, 1, p. 295-300 6 p.

Research output: Contribution to journalArticle

Open Access
Gallic Acid
MCF-7 Cells
ester
Esters
Cells

Synthesis and in vitro antimalarial activity of alkyl esters of gallate as a growth inhibitor of plasmodium falciparum

Arsianti, A., Astuty, H., Fadilah, Simadibrata, D. M., Adyasa, Z. M., Amartya, D., Bahtiar, A., Tanimoto, H. & Kakiuchi, K., 1 Jan 2018, In : Oriental Journal of Chemistry. 34, 2, p. 655-662 8 p.

Research output: Contribution to journalArticle

Growth Inhibitors
Antimalarials
Plasmodium falciparum
Gallic Acid
ester
Catenins
Dextran Sulfate
Nitric Oxide Synthase Type II
Soybeans
Colon

The effect of Mahkota Dewa (Phaleria Macrocarpa) (Scheff.) fruit pericarp extract on COX-2 and β-catenin expression in mice colon induced by dextran sodium sulfate

Kusmardi, Estuningtyas, A., Shavera, D., Tedjo, A., Priosoeryanto, B. P., Habiburrahman, M. & Salinah, 30 Aug 2018, In : Pharmacologyonline. 2, p. 199-205 7 p.

Research output: Contribution to journalArticle

Catenins
Dextran Sulfate
Fruit
Colon
Anti-Inflammatory Agents
2017

Antimalarial effect of flamboyant (Delonix regia) bark and papaya (Carica papaya L) leaf ethanolic extracts against Plasmodium berghei in mice

Fatmawaty, Rosmalena, Amalia, A., Syafitri, I. & Prasasty, V. D., 1 Jan 2017, In : Biomedical and Pharmacology Journal. 10, 3, p. 1081-1089 9 p.

Research output: Contribution to journalArticle

Open Access
Carica
Plasmodium berghei
Antimalarials
Fabaceae
Body Weight

A Simple Photometer and Chemometrics Analysis for Quality Control of Sambiloto (Andrographis paniculata) Raw Material

Heryanto, R., Permana, D., Tedjo, A. & Rohaeti, E., 29 Aug 2017, In : The Journal of Pure and Applied Chemistry Research. 6, 3, p. 238-245

Research output: Contribution to journalArticle

Open Access
Photometers
Quality control
Raw materials
Discriminant analysis
Thin layer chromatography

Cell viability inhibition effect of gallic acid and its synthetic derivative forms on primary cultured endometriosis cells

Arleni, Nareswari, S. S. K., Sopiah, P. P., Zoya, M. A., Arsianti, A. & Muharram, R., 1 Jul 2017, In : Advanced Science Letters. 23, 7, p. 6681-6684 4 p.

Research output: Contribution to journalArticle

Endometriosis
Gallic Acid
Viability
Cultured Cells
Cell Survival
6 Citations (Scopus)
Open Access
Folic Acid Antagonists
Gallic Acid
Computer Simulation
Software
Tetrahydrofolate Dehydrogenase

Design of Emodin Derivative Structures as HBV Capsid Assembly Inhibitor

Firdayani, Yanuar, A., Arsianti, A. & Churiyah, 1 Feb 2017, In : Research Journal of Pharmaceutical, Biological and Chemical Sciences. 8, 1, p. 89-95

Research output: Contribution to journalArticle

Open Access
Emodin
Virus Assembly
Capsid
Viruses
Hepatitis B virus
6 Citations (Scopus)
Open Access
Ageratum
Iodoacetates
Proteoglycans
Matrix Metalloproteinases
Osteoarthritis
2 Citations (Scopus)

Ethanolic extracts of Hedyotis corymbosa L. Improves monosodium iodoacetate-induce osteoarthritis in rat

Bahtiar, A., Sari, F. A., Audina, M., Datunsolang, N. L. C. & Arsianti, A., 1 Mar 2017, In : Asian Journal of Pharmaceutical and Clinical Research. 10, 3, p. 473-476 4 p.

Research output: Contribution to journalArticle

Open Access
Hedyotis
Iodoacetates
Poaceae
Osteoarthritis
Iodoacetic Acid
Open Access
Ageratum
Rheumatoid Arthritis
Indonesia
Osteoclasts
Control Groups
3 Citations (Scopus)

Inhibition of carcinogenesis by seed and soybean meal extract in colon of mice: Apoptosis and dysplasia

Amalia, A. W., Kusmardi, S., Elya, B. & Arsianti, A., 1 Apr 2017, In : Asian Journal of Pharmaceutical and Clinical Research. 10, 4, p. 123-128 6 p.

Research output: Contribution to journalArticle

Open Access
Soybeans
Meals
Seeds
Colon
Carcinogenesis
Open Access
Gallic Acid
Apoptosis Regulatory Proteins
Computer Simulation
Esters
Breast Neoplasms
1 Citation (Scopus)

In silico docking studies of gallic acid structural analogs as Bcl-Xl inhibitor in cancer

Ulfa, D. M., Arsianti, A. & Radji, M., 1 Apr 2017, In : Asian Journal of Pharmaceutical and Clinical Research. 10, 4, p. 119-122 4 p.

Research output: Contribution to journalArticle

Open Access
Gallic Acid
Computer Simulation
Neoplasms
Molecular Docking Simulation
Propyl Gallate
Gallic Acid
Derivatives
Gibbs free energy
Bioactivity
Biological Products

In Silico Screening and Designing Synthesis of Cinchona Alkaloids Derivatives as Potential Anticancer

Hanafi, M., Rosmalena, Prasasty, V. D., Udin, L. Z. & Primahana, G., 1 Apr 2017, In : The Journal of Tropical Life Science. 7, 2, p. 121-127

Research output: Contribution to journalArticle

Open Access
Cinchona Alkaloids
Screening
P-Glycoprotein
Derivatives
P-Glycoproteins
Open Access
Eugenol
HT29 Cells
Gallic Acid
Esterification
Computer Simulation
1 Citation (Scopus)

In silico study and cytotoxicity of the synthesized open-chain analogues of antimycin A3 against HEP-2 laryngeal cancer cells

Arsianti, A., Fadilah, Kusmardi, Sugiarta, G. Y., Tanimoto, H. & Kakiuchi, K., 1 Aug 2017, In : Current Cancer Therapy Reviews. 13, 2, p. 129-136 8 p.

Research output: Contribution to journalArticle

Laryngeal Neoplasms
Computer Simulation
Drug Therapy
Esterification
Threonine
1 Citation (Scopus)
Open Access
Eugenol
Computer Simulation
Colorectal Neoplasms
Apoptosis
Ligands

In Silico Study of Gallic Acid Derivatives as Novel Antiviral Agents of Hepatitis C

Arsianti, A., Fadilah, Bahtiar, A., Dwira, S. & Apriyanto, D. R., 1 Dec 2017, In : International Journal of ChemTech Research. 10, 3, p. 11-117

Research output: Contribution to journalArticle

Open Access
Gallic Acid
Antiviral Agents
Derivatives
Virus Receptors
Threonine
1 Citation (Scopus)
HCT116 Cells
Eugenol
Benzoates
Colon
Colonic Neoplasms
Open Access
Inhibitor of Apoptosis Proteins
Amides
Computer Simulation
Apoptosis
B-Cell Lymphoma

Structure-based drug design of quercetin and its derivatives against HMGB1

Simanjuntak, K., Simanjuntak, J. E., Rosmalena & Prasasty, V. D., 1 Jan 2017, In : Biomedical and Pharmacology Journal. 10, 4, p. 1973-1982 10 p.

Research output: Contribution to journalArticle

Open Access
Drug Design
Quercetin
Neoplasms
Carcinogenesis
Pharmacology

The apoptotic effect of gallic acid and its derivatives on primary cultured endometriosis cells

Arleni, Dachniar, H., Adyasa, Z. M., Nareswari, S. S. K., Sopiah, P., Arsianti, A. & Natadisastra, R. M., 1 Jul 2017, In : Advanced Science Letters. 23, 7, p. 6697-6700 4 p.

Research output: Contribution to journalArticle

Endometriosis
Gallic Acid
Cultured Cells
Apoptosis
apoptosis
Open Access
Dextran Sulfate
Nitric Oxide Synthase Type II
Fruit
Colon
Anti-Inflammatory Agents
2 Citations (Scopus)
Open Access
Punicaceae
Dextran Sulfate
Indonesia
Cyclooxygenase 2
Colon
2016
8 Citations (Scopus)

Anti-hepatitis c virus activity of a crude extract from longan (Dimocarpus longan Lour.) leaves

Apriyanto, D. R., Aoki, C., Hartati, S., Hanafi, M., Kardono, L. B. S., Arsianti, A., Louisa, M., Sudiro, T. M., Dewi, B. E., Sudarmono, P. P., Kusumo, A. S. W. & Hotta, H., 1 Jan 2016, In : Japanese Journal of Infectious Diseases. 69, 3, p. 213-220 8 p.

Research output: Contribution to journalArticle

Open Access
Hepatitis Viruses
Complex Mixtures
Hepacivirus
Protease Inhibitors
Virus Diseases
4 Citations (Scopus)
Caspase Inhibitors
Colorectal Neoplasms
Amides
Apoptosis
Caspases
5 Citations (Scopus)

Phytochemical composition and anticancer activity of seaweeds Ulva lactuca and Eucheuma cottonii against breast MCF-7 and colon HCT-116 cells

Arsianti, A., Fadilah, Fatmawaty, Wibisono, L. K., Kusmardi, S., Azizah, N. N., Putrianingsih, R., Murniasih, T., Rasyid, A. & Pangestuti, R., 1 Nov 2016, In : Asian Journal of Pharmaceutical and Clinical Research. 9, 6, p. 115-119 5 p.

Research output: Contribution to journalArticle

Open Access
Ulva
HCT116 Cells
Seaweed
Phytochemicals
Colon